ORCHESTRATED REGULATION OF NOGO RECEPTORS, LOTUS, AMPA RECEPTORS AND BDNF IN AN ECT MODEL SUGGESTS OPENING AND CLOSURE OF A WINDOW OF SYNAPTIC PLASTICITY.

Orchestrated regulation of Nogo receptors, LOTUS, AMPA receptors and BDNF in an ECT model suggests opening and closure of a window of synaptic plasticity.

Electroconvulsive therapy (ECT) is an efficient and relatively fast acting treatment for depression.However, one severe side effect of the treatment is retrograde amnesia, which datrex life rafts in certain cases can be long-term.The mechanisms behind the antidepressant effect and the amnesia are not well understood.We hypothesized that ECT causes

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Safety, Tolerability, and Dose-Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis: Protocol for a Phase 1 Clinical Trial to Determine Safety and Identify Side Effects

BackgroundChronic abdominal pain is the hallmark symptom of chronic pancreatitis (CP), with 50% to 80% of patients seeking medical attention for pain control.Although several management options are available, outcomes are often disappointing, and opioids remain a mainstay of therapy.Opioid-induced hyperalgesia is a phenomenon resulting in dose esca

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